Bernard Halloran, PhD

Adjunct Professor and Lecturer

Major programs in Dr. Halloran's laboratory include stem cell aging using animal models to study the effects of aging on stem cells and bone. Projects include work with natural products from fruits for the treatment of osteoporosis, development of orthopedic stem cell-based devices to facilitate spine fusion and bone healing. Students and postdoctoral fellows are encouraged to work collaboratively with other faculty in the Departments of Medicine, Bioengineering and Orthopedics.

Education
Postdoc, 1980 - Bone, vitamin D, University of Wisconsin
Postdoc, 1977 - Electron microbeam analysis, University of Chicago
PhD, 1976 - Biophysics, University of Rochester
MS, 1972 - Physics, Montana State University
BS, 1969 - Physics, Gonzaga University
Websites
Publications

  1. Chen JV, Lee K, Tillinghast K, Halloran B, Dang ABC. Locally Delivered Ascorbic Acid and β-Glycerophosphate Augment Local Bone Graft in a Murine Model of 2-Level Posterior Spinal Fusion. International journal of spine surgery 2021. PMID: 34649952


  2. Liu X, Liu M, Turner R, Iwaniec U, Kim H, Halloran B. Dried plum mitigates spinal cord injury-induced bone loss in mice. JOR spine 2020. PMID: 33392451


  3. Steczina S, Tahimic CGT, Pendleton M, M'Saad O, Lowe M, Alwood JS, Halloran BP, Globus RK, Schreurs AS. Dietary countermeasure mitigates simulated spaceflight-induced osteopenia in mice. Scientific Reports 2020. PMID: 32300161


  4. Dolores M Shoback, Hunter Heath, Daniel D Bikle, Wenhan Chang, Bernard Halloran, Gordon Strewler, Robert Nissenson. Claude D Arnaud, Jr, MD (1929–2016): ASBMR Loses a Founding Father. Journal of Bone and Mineral Research 2016. PMID:


  5. Shahnazari M, Turner RT, Iwaniec UT, Wronski TJ, Li M, Ferruzzi MG, Nissenson RA, Halloran BP. Dietary dried plum increases bone mass, suppresses proinflammatory cytokines and promotes attainment of peak bone mass in male mice. The Journal of nutritional biochemistry 2016. PMID: 27239754


  6. Schreurs AS, Shirazi-Fard Y, Shahnazari M, Alwood JS, Truong TA, Tahimic CG, Limoli CL, Turner ND, Halloran B, Globus RK. Dried plum diet protects from bone loss caused by ionizing radiation. Scientific Reports 2016. PMID: 26867002


  7. Mohammad Shahnazari, Bernard Halloran. Dietary Dried Plum Increases Peak Bone Mass. Nutritional Influences on Bone Health 2016. PMID:


  8. Wang L, Carroll DO, Liu X, Roth T, Kim H, Halloran B, Nissenson RA. Effects of blockade of endogenous Gi signaling in Tie2-expressing cells on bone formation in a mouse model of heterotopic ossification. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015. PMID: 25773760


  9. Kang H, Dang AB, Joshi SK, Halloran B, Nissenson R, Zhang X, Li J, Kim HT, Liu X. Novel mouse model of spinal cord injury-induced heterotopic ossification. Journal of rehabilitation research and development 2014. PMID: 25436890


  10. Smith BJ, Graef JL, Wronski TJ, Rendina E, Williams AA, Clark KA, Clarke SL, Lucas EA, Halloran BP. Effects of dried plum supplementation on bone metabolism in adult C57BL/6 male mice. Calcified tissue international 2013. PMID: 24357047


  11. Liu X, Kang H, Shahnazari M, Kim H, Wang L, Larm O, Adolfsson L, Nissenson R, Halloran B. A novel mouse model of trauma induced heterotopic ossification. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2013. PMID: 24136593


  12. Shahnazari M, Chu V, Wronski TJ, Nissenson RA, Halloran BP. CXCL12/CXCR4 signaling in the osteoblast regulates the mesenchymal stem cell and osteoclast lineage populations. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013. PMID: 23704087


  13. Rendina E, Hembree KD, Davis MR, Marlow D, Clarke SL, Halloran BP, Lucas EA, Smith BJ. Dried plum's unique capacity to reverse bone loss and alter bone metabolism in postmenopausal osteoporosis model. PloS one 2013. PMID: 23555991


  14. Shahnazari M, Kurimoto P, Boudignon BM, Orwoll BE, Bikle DD, Halloran BP. Simulated spaceflight produces a rapid and sustained loss of osteoprogenitors and an acute but transitory rise of osteoclast precursors in two genetic strains of mice. American journal of physiology. Endocrinology and metabolism 2012. PMID: 23047986


  15. Shahnazari M, Wronski T, Chu V, Williams A, Leeper A, Stolina M, Ke HZ, Halloran B. Early response of bone marrow osteoprogenitors to skeletal unloading and sclerostin antibody. Calcified tissue international 2012. PMID: 22644321


  16. Long RK, Nishida S, Kubota T, Wang Y, Sakata T, Elalieh HZ, Halloran BP, Bikle DD. Skeletal unloading-induced insulin-like growth factor 1 (IGF-1) nonresponsiveness is not shared by platelet-derived growth factor: the selective role of integrins in IGF-1 signaling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011. PMID: 21932337


  17. Shahnazari M, Dwyer D, Chu V, Asuncion F, Stolina M, Ominsky M, Kostenuik P, Halloran B. Bone turnover markers in peripheral blood and marrow plasma reflect trabecular bone loss but not endocortical expansion in aging mice. Bone 2011. PMID: 22154841


  18. Brenda Jane Smith, Kelsey Hembree, Elizabeth Rendina, Yan Wang, Denver Marlow, Stephen L. Clarke, Bernard P. Halloran, Edralin A. Lucas. Comparative Study of Dried Fruits and Their Ability to Restore Bone Microarchitecture in Osteopenic C57BL/6 Mice. The FASEB Journal 2011. PMID:


  19. Halloran BP, Wronski TJ, VonHerzen DC, Chu V, Xia X, Pingel JE, Williams AA, Smith BJ. Dietary dried plum increases bone mass in adult and aged male mice. The Journal of nutrition 2010. PMID: 20739449


  20. Hsiao EC, Boudignon BM, Halloran BP, Nissenson RA, Conklin BR. Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation. Volume 25 of Issue 3. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010. PMID: 20200944


  21. Wang L, Shi X, Zhao R, Halloran BP, Clark DJ, Jacobs CR, Kingery WS. Calcitonin-gene-related peptide stimulates stromal cell osteogenic differentiation and inhibits RANKL induced NF-kappaB activation, osteoclastogenesis and bone resorption. Bone 2009. PMID: 19962460


  22. Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Bone 2009. PMID: 19379851


  23. Hsiao EC, Boudignon BM, Chang WC, Bencsik M, Peng J, Nguyen TD, Manalac C, Halloran BP, Conklin BR, Nissenson RA. Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. Volume 105 of Issue 4. Proceedings of the National Academy of Sciences of the United States of America 2008. PMID: 18212126


  24. BERNARD HALLORAN, DANIEL D. BIKLE. CHAPTER 46 Mechanisms of Immobilization-Induced Bone Loss. 2008. PMID:


  25. Roger K. Long, Bernard P. Halloran, Daniel D. Bikle. Integrin Regulation of the IGF-I Receptor in Bone, and the Response to Load. Clinical Reviews in Bone and Mineral Metabolism 2007. PMID:


  26. Peng J, Bencsik M, Louie A, Lu W, Millard S, Nguyen P, Burghardt A, Majumdar S, Wronski TJ, Halloran B, Conklin BR, Nissenson RA. Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia. Volume 149 of Issue 3. Endocrinology 2007. PMID: 18048501


  27. Wang Y, Nishida S, Boudignon BM, Burghardt A, Elalieh HZ, Hamilton MM, Majumdar S, Halloran BP, Clemens TL, Bikle DD. IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007. PMID: 17539737


  28. Cao JJ, Kurimoto P, Boudignon B, Rosen C, Lima F, Halloran BP. Aging impairs IGF-I receptor activation and induces skeletal resistance to IGF-I. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007. PMID: 17488198


  29. Boudignon BM, Bikle DD, Kurimoto P, Elalieh H, Nishida S, Wang Y, Burghardt A, Majumdar S, Orwoll BE, Rosen C, Halloran BP. Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloading. Journal of applied physiology (Bethesda, Md. : 1985) 2007. PMID: 17412794


  30. Wang Y, Nishida S, Elalieh HZ, Long RK, Halloran BP, Bikle DD. Role of IGF-I signaling in regulating osteoclastogenesis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006. PMID: 16939393


  31. Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD. Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology 2006. PMID: 16857753


  32. Kazakia GJ, Nauman EA, Ebenstein DM, Halloran BP, Keaveny TM. Effects of in vitro bone formation on the mechanical properties of a trabeculated hydroxyapatite bone substitute. Journal of biomedical materials research. Part A 2006. PMID: 16514602


  33. Wang Y, Sakata T, Elalieh HZ, Munson SJ, Burghardt A, Majumdar S, Halloran BP, Bikle DD. Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I. The Journal of endocrinology 2006. PMID: 16648295


  34. Benjamin Boudignon, Pam Kurimoto, Shigeki Nishida, Yongmei Wang, Jay Cao, Hashem Elalieh, Daniel Bikle, Bernard Halloran. IGF-I enhances bone recovery after 2 weeks of unloading. 2006. PMID:


  35. Roger K Long, T Sakata, H Z Elalieh, B P Halloran, D D Bikle. Regulation of IGF-1 signaling by integrins in bone: Role of mechanical loading. 2006. PMID:


  36. Yongmei Wang, Shigeki Nishida, Hashem Z Elalieh, Roger K Long, Bernard P Halloran, Daniel D Bikle. The Role of IGF-I Signaling in Regulating Osteoclastogenesis. 2006. PMID:


  37. A. A. Portale, B. P. Halloran, S. T. Harris, D. D. Bikle, R. C. Morris. Metabolic acidosis reverses the increase in serum 1,25(OH)2D in phosphorus-restricted normal men. AJP Endocrinology and Metabolism 2006. PMID:


  38. Cao JJ, Wronski TJ, Iwaniec U, Phleger L, Kurimoto P, Boudignon B, Halloran BP. Aging increases stromal/osteoblastic cell-induced osteoclastogenesis and alters the osteoclast precursor pool in the mouse. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005. PMID: 16059637


  39. BERNARD P. HALLORAN, ANTHONY A. PORTALE. CHAPTER 50 Vitamin D Metabolism and Aging. Vitamin D 2005. PMID:


  40. Cao JJ, Singleton PA, Majumdar S, Boudignon B, Burghardt A, Kurimoto P, Wronski TJ, Bourguignon LY, Halloran BP. Hyaluronan increases RANKL expression in bone marrow stromal cells through CD44. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004. PMID: 15619667


  41. Sakata T, Wang Y, Halloran BP, Elalieh HZ, Cao J, Bikle DD. Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003. PMID: 15040832


  42. Huang JC, Sakata T, Pfleger LL, Bencsik M, Halloran BP, Bikle DD, Nissenson RA. PTH differentially regulates expression of RANKL and OPG. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003. PMID: 14969393


  43. Nauman EA, Sakata T, Keaveny TM, Halloran BP, Bikle DD. bFGF administration lowers the phosphate threshold for mineralization in bone marrow stromal cells. Calcified tissue international 2003. PMID: 14565596


  44. Sakata T, Halloran BP, Elalieh HZ, Munson SJ, Rudner L, Venton L, Ginzinger D, Rosen CJ, Bikle DD. Skeletal unloading induces resistance to insulin-like growth factor I on bone formation. Bone 2003. PMID: 12810174


  45. Bikle DD, Sakata T, Halloran BP. The impact of skeletal unloading on bone formation. Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology 2003. PMID: 12959131


  46. Cao J, Venton L, Sakata T, Halloran BP. Expression of RANKL and OPG correlates with age-related bone loss in male C57BL/6 mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003. PMID: 12568404


  47. Nauman EA, Ebenstein DM, Hughes KF, Pruitt L, Halloran BP, Bikle DD, Keaveny TM. Mechanical and chemical characteristics of mineral produced by basic fibroblast growth factor-treated bone marrow stromal cells in vitro. Tissue engineering 2002. PMID: 12542939


  48. Bikle DD, Sakata T, Leary C, Elalieh H, Ginzinger D, Rosen CJ, Beamer W, Majumdar S, Halloran BP. Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002. PMID: 12211426


  49. Halloran BP, Ferguson VL, Simske SJ, Burghardt A, Venton LL, Majumdar S. Changes in bone structure and mass with advancing age in the male C57BL/6J mouse. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002. PMID: 12054159


  50. Kahn AJ, Halloran B, Wolkowitz O, Brizendine L. Dehydroepiandrosterone supplementation and bone turnover in middle-aged to elderly men. The Journal of clinical endocrinology and metabolism 2002. PMID: 11932279


  51. Halloran B, Udén P, Duh QY, Kikuchi S, Wieder T, Cao J, Clark O. Parathyroid gland volume increases with postmaturational aging in the rat. American journal of physiology. Endocrinology and metabolism 2002. PMID: 11832357


  52. Bikle D, Majumdar S, Laib A, Powell-Braxton L, Rosen C, Beamer W, Nauman E, Leary C, Halloran B. The skeletal structure of insulin-like growth factor I-deficient mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001. PMID: 11760848


  53. Vajda EG, Wronski TJ, Halloran BP, Bachus KN, Miller SC. Spaceflight alters bone mechanics and modeling drifts in growing rats. Aviation, space, and environmental medicine 2001. PMID: 11506233


  54. Rabkin BA, Szivek JA, Schonfeld JE, Halloran BP. Long-term measurement of bone strain in vivo: the rat tibia. Journal of biomedical materials research 2001. PMID: 11319741


  55. Nauman EA, Satcher RL, Keaveny TM, Halloran BP, Bikle DD. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization. Journal of applied physiology (Bethesda, Md. : 1985) 2001. PMID: 11299276


  56. Morey-Holton ER, Halloran BP, Garetto LP, Doty SB. Animal housing influences the response of bone to spaceflight in juvenile rats. Journal of applied physiology (Bethesda, Md. : 1985) 2000. PMID: 10749823


  57. Dehority W, Halloran BP, Bikle DD, Curren T, Kostenuik PJ, Wronski TJ, Shen Y, Rabkin B, Bouraoui A, Morey-Holton E. Bone and hormonal changes induced by skeletal unloading in the mature male rat. The American journal of physiology 1999. PMID: 9886951


  58. Bernard P. Halloran, Daniel D. Bikle. Chapter 10 Age-Related Changes in Mineral Metabolism. Osteoporosis in Men 1999. PMID:


  59. Kostenuik PJ, Harris J, Halloran BP, Turner RT, Morey-Holton ER, Bikle DD. Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999. PMID: 9893062


  60. Bikle DD, Halloran BP. The response of bone to unloading. Journal of bone and mineral metabolism 1999. PMID: 10575587


  61. Russell T. Turner, Glenda L. Evans, Jason M. Cavolina, Bernard Halloran, Emily Morey-Holton. Programmed Administration of Parathyroid Hormone Increases Bone Formation and Reduces Bone Loss in Hindlimb-Unloaded Ovariectomized Rats**This work was supported by NASA Grants NAGW-4963 and NCC-2–589. Additional support was obtained from NIH Grants AR- Endocrinology 1998. PMID:


  62. Turner RT, Evans GL, Cavolina JM, Halloran B, Morey-Holton E. Programmed administration of parathyroid hormone increases bone formation and reduces bone loss in hindlimb-unloaded ovariectomized rats. Endocrinology 1998. PMID: 9751486


  63. Wronski TJ, Li M, Shen Y, Miller SC, Bowman BM, Kostenuik P, Halloran BP. Lack of effect of spaceflight on bone mass and bone formation in group-housed rats. Journal of applied physiology (Bethesda, Md. : 1985) 1998. PMID: 9655787


  64. Ritchie LD, Fung EB, Halloran BP, Turnlund JR, Van Loan MD, Cann CE, King JC. A longitudinal study of calcium homeostasis during human pregnancy and lactation and after resumption of menses. The American journal of clinical nutrition 1998. PMID: 9537616


  65. Kostenuik PJ, Halloran BP, Morey-Holton ER, Bikle DD. Skeletal unloading inhibits the in vitro proliferation and differentiation of rat osteoprogenitor cells. The American journal of physiology 1997. PMID: 9435529


  66. Halloran BP, Bikle DD, Harris J, Tanner S, Curren T, Morey-Holton E. Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997. PMID: 9200006


  67. Bikle DD, Halloran BP, Morey-Holton E. Spaceflight and the skeleton: lessons for the earthbound. Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology 1997. PMID: 11540113


  68. Portale AA, Lonergan ET, Tanney DM, Halloran BP. Aging alters calcium regulation of serum concentration of parathyroid hormone in healthy men. The American journal of physiology 1997. PMID: 9038863


  69. Bikle DD, Halloran BP, Morey-Holton E. Space flight and the skeleton: lessons for the earthbound. The Endocrinologist 1997. PMID: 11540416


  70. Li M, Shen Y, Halloran BP, Baumann BD, Miller K, Wronski TJ. Skeletal response to corticosteroid deficiency and excess in growing male rats. Bone 1996. PMID: 8853849


  71. B. P. Halloran. Aging and renal responsiveness to parathyroid hormone in healthy men. 1996. PMID:


  72. Halloran BP, Lonergan ET, Portale AA. Aging and renal responsiveness to parathyroid hormone in healthy men. The Journal of clinical endocrinology and metabolism 1996. PMID: 8964850


  73. Portale AA, Halloran BP, Morris RC, Lonergan ET. Effect of aging on the metabolism of phosphorus and 1,25-dihydroxyvitamin D in healthy men. The American journal of physiology 1996. PMID: 8638697


  74. Halloran BP, Bikle DD, Harris J, Autry CP, Currier PA, Tanner S, Patterson-Buckendahl P, Morey-Holton E. Skeletal unloading induces selective resistance to the anabolic actions of growth hormone on bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995. PMID: 8585419


  75. Bikle DD, Harris J, Halloran BP, Currier PA, Tanner S, Morey-Holton E. The molecular response of bone to growth hormone during skeletal unloading: regional differences. Endocrinology 1995. PMID: 7720659


  76. D D Bikle, J Harris, B P Halloran, P A Currier, S Tanner, E Morey-Holton. The molecular response of bone to growth hormone during skeletal unloading: regional differences. Endocrinology 1995. PMID:


  77. Bikle DD, Harris J, Halloran BP, Morey-Holton E. Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation. The American journal of physiology 1994. PMID: 7810622


  78. Bikle DD, Morey-Holton ER, Doty SB, Currier PA, Tanner SJ, Halloran BP. Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994. PMID: 7863829


  79. Bikle DD, Harris J, Halloran BP, Morey-Holton ER. Skeletal unloading induces resistance to insulin-like growth factor I. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994. PMID: 7532347


  80. Bikle DD, Harris J, Halloran BP, Roberts CT, Leroith D, Morey-Holton E. Expression of the genes for insulin-like growth factors and their receptors in bone during skeletal growth. The American journal of physiology 1994. PMID: 8074208


  81. Bikle DD, Halloran BP, Morey-Holton E. Impact of skeletal unloading on bone formation: role of systemic and local factors. Acta astronautica 1994. PMID: 11539511


  82. Bikle DD, Halloran BP, Riviere JE. Production of 1,25 dihydroxyvitamin D3 by perfused pig skin. The Journal of investigative dermatology 1994. PMID: 8176265


  83. Halloran BP. Cellular growth and differentiation during embryogenesis and fetal development. The role of vitamin D. Advances in experimental medicine and biology 1994. PMID: 7832052


  84. Bikle DD, Stesin A, Halloran B, Steinbach L, Recker R. Alcohol-induced bone disease: relationship to age and parathyroid hormone levels. Alcoholism, clinical and experimental research 1993. PMID: 8333602


  85. Halloran BP, Bikle DD, Harris J, Foskett HC, Morey-Holton E. Skeletal unloading decreases production of 1,25-dihydroxyvitamin D. The American journal of physiology 1993. PMID: 8498493


  86. Bikle DD, Halloran B, Fong L, Steinbach L, Shellito J. Elevated 1,25-dihydroxyvitamin D levels in patients with chronic obstructive pulmonary disease treated with prednisone. The Journal of clinical endocrinology and metabolism 1993. PMID: 8432789


  87. Portale AA, Halloran BP, Harris ST, Bikle DD, Morris RC. Metabolic acidosis reverses the increase in serum 1,25(OH)2D in phosphorus-restricted normal men. The American journal of physiology 1992. PMID: 1476189


  88. Bikle DD, Halloran BP, Harris ST, Portale AA. Progestin antagonism of estrogen stimulated 1,25-dihydroxyvitamin D levels. The Journal of clinical endocrinology and metabolism 1992. PMID: 1639954


  89. Wada L, Daly R, Kern D, Halloran B. Kinetics of 1,25-dihydroxyvitamin D metabolism in the aging rat. The American journal of physiology 1992. PMID: 1616024


  90. A.A. Portale, B.P. Halloran, E.T. Lonergan, R.C. Morris. Effect of aging on the circadian rhythm in serum concentration of phosphorus in healthy men. Bone and mineral 1992. PMID:


  91. Bernard P. Halloran, Daniel D. Bikle, Steven T. Harris, Anthony A. Portale. EFFECTS OF 17B-ESTRADIOL AND MEDROXYPROGESTERONE ON THE SERUM CONCENTRATION OF 1,25-DIHYDROXYVITAMIN D IN PERI-MENOPAUSAL WOMEN. Vitamin D 1991. PMID:


  92. Grady D, Halloran B, Cummings S, Leveille S, Wells L, Black D, Byl N. 1,25-Dihydroxyvitamin D3 and muscle strength in the elderly: a randomized controlled trial. The Journal of clinical endocrinology and metabolism 1991. PMID: 1939527


  93. Stein B, Halloran BP, Reinhardt T, Engstrom GW, Bales CW, Drezner MK, Currie KL, Takizawa M, Adams JS, Epstein S. Cyclosporin-A increases synthesis of 1,25-dihydroxyvitamin D3 in the rat and mouse. Endocrinology 1991. PMID: 1999158


  94. Bikle DD, Halloran BP, McGalliard-Cone C, Morey-Holton E. Different responses of trabecular and cortical bone to 1,25(OH)2D3 infusion. The American journal of physiology 1990. PMID: 2240210


  95. Halloran BP, Portale AA, Lonergan ET, Morris RC. Production and metabolic clearance of 1,25-dihydroxyvitamin D in men: effect of advancing age. The Journal of clinical endocrinology and metabolism 1990. PMID: 2298850


  96. Sessions ND, Halloran BP, Bikle DD, Wronski TJ, Cone CM, Morey-Holton E. Bone response to normal weight bearing after a period of skeletal unloading. The American journal of physiology 1989. PMID: 2801939


  97. Halloran BP. Is 1,25-dihydroxyvitamin D required for reproduction? Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1989. PMID: 2662198


  98. Portale AA, Halloran BP, Morris RC. Physiologic regulation of the serum concentration of 1,25-dihydroxyvitamin D by phosphorus in normal men. The Journal of clinical investigation 1989. PMID: 2708521


  99. Halloran BP, Castro ME. Vitamin D kinetics in vivo: effect of 1,25-dihydroxyvitamin D administration. The American journal of physiology 1989. PMID: 2785765


  100. Halloran BP, Bikle DD, Castro ME, Gee E. Isotopic labeling affects 1,25-dihydroxyvitamin D metabolism. Biochemistry 1989. PMID: 2713363


  101. Halloran BP, Bikle DD, Cone CM, Morey-Holton E. Glucocorticoids and inhibition of bone formation induced by skeletal unloading. The American journal of physiology 1988. PMID: 3202163


  102. Halloran BP, Spencer EM. Dietary phosphorus and 1,25-dihydroxyvitamin D metabolism: influence of insulin-like growth factor I. Endocrinology 1988. PMID: 3402383


  103. A.A. PORTALE, ?.P. HALLORAN, E.T. LONERGAN, R.C. MORRIS. RESPONSE OF THE SERUM LEVEL OF 1,25-(OH)2D TO RESTRICTION OF DIETARY PHOSPHORUS: EFFECT OF ADVANCED AGE. Vitamin D 1988. PMID:


  104. Portale AA, Halloran BP, Morris RC. Dietary intake of phosphorus modulates the circadian rhythm in serum concentration of phosphorus. Implications for the renal production of 1,25-dihydroxyvitamin D. The Journal of clinical investigation 1987. PMID: 3654974


  105. Feingold KR, Williams ML, Pillai S, Menon GK, Halloran BP, Bikle DD, Elias PM. The effect of vitamin D status on cutaneous sterologenesis in vivo and in vitro. Biochimica et biophysica acta 1987. PMID: 3040120


  106. Bikle DD, Halloran BP, Cone CM, Globus RK, Morey-Holton E. The effects of simulated weightlessness on bone maturation. Endocrinology 1987. PMID: 3803298


  107. Wronski TJ, Halloran BP, Bikle DD, Globus RK, Morey-Holton ER. Chronic administration of 1,25-dihydroxyvitamin D3: increased bone but impaired mineralization. Endocrinology 1986. PMID: 3780540


  108. Bikle DD, Gee E, Halloran B, Kowalski MA, Ryzen E, Haddad JG. Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. The Journal of clinical endocrinology and metabolism 1986. PMID: 3745408


  109. Halloran BP, Bikle DD, Levens MJ, Castro ME, Globus RK, Holton E. Chronic 1,25-dihydroxyvitamin D3 administration in the rat reduces the serum concentration of 25-hydroxyvitamin D by increasing metabolic clearance rate. The Journal of clinical investigation 1986. PMID: 3489007


  110. Bikle DD, Halloran BP, Gee E, Ryzen E, Haddad JG. Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels. The Journal of clinical investigation 1986. PMID: 3745436


  111. Strewler GJ, Wronski TJ, Halloran BP, Miller SC, Leung SC, Williams RD, Nissenson RA. Pathogenesis of hypercalcemia in nude mice bearing a human renal carcinoma. Endocrinology 1986. PMID: 3013591


  112. Globus RK, Bikle DD, Halloran B, Morey-Holton E. Skeletal response to dietary calcium in a rat model simulating weightlessness. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986. PMID: 3503537


  113. Halloran BP, Bikle DD, Wronski TJ, Globus RK, Levens MJ, Morey-Holton E. The role of 1,25-dihydroxyvitamin D in the inhibition of bone formation induced by skeletal unloading. Endocrinology 1986. PMID: 3485043


  114. Portale AA, Halloran BP, Murphy MM, Morris RC. Oral intake of phosphorus can determine the serum concentration of 1,25-dihydroxyvitamin D by determining its production rate in humans. The Journal of clinical investigation 1986. PMID: 3753709


  115. Halloran BP, Bikle DD, Wronski TJ, Globus RK, Levens MJ, Morey-Holton E. Effect of simulated weightlessness and chronic 1,25-dihydroxyvitamin D administration on bone metabolism. The Physiologist 1985. PMID: 3841737


  116. Hulter HN, Halloran BP, Toto RD, Peterson JC. Long-term control of plasma calcitriol concentration in dogs and humans. Dominant role of plasma calcium concentration in experimental hyperparathyroidism. The Journal of clinical investigation 1985. PMID: 3928683


  117. Bikle DD, Genant HK, Cann C, Recker RR, Halloran BP, Strewler GJ. Bone disease in alcohol abuse. Annals of internal medicine 1985. PMID: 2988390


  118. Halloran BP, Portale AA, Castro M, Morris RC, Goldsmith RS. Serum concentration of 1,25-dihydroxyvitamin D in the human: diurnal variation. The Journal of clinical endocrinology and metabolism 1985. PMID: 3998063


  119. Bikle DD, Halloran BP, Whitney JO, Hollis BW. Measurement of 25,26-dihydroxyvitamin D: importance of the configuration of the C-25 hydroxyl group. Biochemistry 1984. PMID: 6543324


  120. Bikle DD, Gee E, Halloran B, Haddad JG. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. The Journal of clinical investigation 1984. PMID: 6549014


  121. Halloran BP, Schaefer P, Lifschitz M, Levens M, Goldsmith RS. Plasma vitamin D metabolite concentrations in chronic renal failure: effect of oral administration of 25-hydroxyvitamin D3. The Journal of clinical endocrinology and metabolism 1984. PMID: 6333430


  122. Halloran BP, Bikle DD, Whitney JO. Separation of isotopically labeled vitamin D metabolites by high-performance liquid chromatography. Journal of chromatography 1984. PMID: 6511833


  123. Portale AA, Booth BE, Halloran BP, Morris RC. Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency. The Journal of clinical investigation 1984. PMID: 6547151


  124. Armbrecht HJ, Forte LR, Halloran BP. Effect of age and dietary calcium on renal 25(OH)D metabolism, serum 1,25(OH)2D, and PTH. The American journal of physiology 1984. PMID: 6608276


  125. Gogel E, Halloran BP, Strewler GJ. Probenecid inhibits the secretion of nephrogenous adenosine 3',5'-monophosphate in normal man. The Journal of clinical endocrinology and metabolism 1983. PMID: 6309880


  126. Miller SC, Halloran BP, DeLuca HF, Jee WS. Studies on the role of vitamin D in early skeletal development, mineralization, and growth in rats. Calcified tissue international 1983. PMID: 6616315


  127. Stern PH, Halloran BP, DeLuca HF, Hefley TJ. Responsiveness of vitamin D-deficient fetal rat limb bones to parathyroid hormone in culture. The American journal of physiology 1983. PMID: 6687660


  128. Bikle DD, Herman RH, Hull S, Hagler L, Harris D, Halloran B. Adaptive response of humans to changes in dietary calcium: relationship between vitamin D regulated intestinal function and serum 1,25-dihydroxyvitamin D levels. Gastroenterology 1983. PMID: 6687358


  129. Bernard P. Halloran. Radioimmunoassay of the Vitamin D Metabolites. Assay of Calcium-regulating Hormones 1983. PMID:


  130. Miller SC, Halloran BP, DeLuca HF, Jee WS. Role of vitamin D in maternal skeletal changes during pregnancy and lactation: a histomorphometric study. Calcified tissue international 1982. PMID: 6809285


  131. DeLuca HF, Franceschi RT, Halloran BP, Massaro ER. Molecular events involved in 1,25-dihydroxyvitamin D3 stimulation of intestinal calcium transport. Federation proceedings 1982. PMID: 6276233


  132. Halloran BP, DeLuca HF. Appearance of the intestinal cytosolic receptor for 1,25-dihydroxyvitamin D3 during neonatal development in the rat. The Journal of biological chemistry 1981. PMID: 6265444


  133. Halloran BP, DeLuca HF, Barthell E, Yamada S, Ohmori M, Takayama H. An examination of the importance of 24-hydroxylation to the function of vitamin D during early development. Endocrinology 1981. PMID: 6894423


  134. Halloran BP, De Luca HF. Effect of vitamin D deficiency on skeletal development during early growth in the rat. Archives of biochemistry and biophysics 1981. PMID: 7283447


  135. Halloran BP, De Luca HF. Intestinal calcium transport: evidence for two distinct mechanisms of action of 1,25-dihydroxyvitamin D3. Archives of biochemistry and biophysics 1981. PMID: 6894839


  136. Miller SC, Halloran BP, DeLuca HF, Yamada S, Takayama H, Jee WS. Studies on the role of 24-hydroxylation of vitamin D in the mineralization of cartilage and bone of vitamin D-deficient rats. Calcified tissue international 1981. PMID: 6274486


  137. Halloran BP, DeLuca HF. Calcium transport in small intestine during early development: role of vitamin D. The American journal of physiology 1980. PMID: 7446740


  138. Halloran BP, DeLuca HF. Skeletal changes during pregnancy and lactation: the role of vitamin D. Endocrinology 1980. PMID: 7428698


  139. Halloran BP, DeLuca HF. Effect of vitamin D deficiency on fertility and reproductive capacity in the female rat. The Journal of nutrition 1980. PMID: 7400847


  140. Halloran BP, DeLuca HF. Calcium transport in small intestine during pregnancy and lactation. The American journal of physiology 1980. PMID: 6249126


  141. Halloran BP, DeLuca HF, Vincenzi FF. (Ca2+ + Mg2+)-ATPase and calmodulin activity of rat red blood cells: lack of dependence on vitamin D. FEBS letters 1980. PMID: 6445833


  142. Halloran BP, Barthell EN, DeLuca HF. Vitamin D metabolism during pregnancy and lactation in the rat. Proceedings of the National Academy of Sciences of the United States of America 1979. PMID: 293660


  143. Tanaka Y, Halloran B, Schnoes HK, DeLuca HF. In vitro production of 1,25-dihydroxyvitamin D3 by rat placental tissue. Proceedings of the National Academy of Sciences of the United States of America 1979. PMID: 291919


  144. Halloran BP, DeLuca HF. Vitamin D deficiency and reproduction in rats. Science (New York, N.Y.) 1979. PMID: 432628