Bilal Hameed, MBBS

Professor

I am a Professor of Medicine and Ambulatory Director of Hepatology. I was the program director for transplant hepatology fellowship. Beside busy clinically my research interest includes nonalcoholic steatohepatitis, PSC, ALF, HCC and cirrhosis. I am the co-PI for NIH funded Liver Cirrhosis Network (LCN) and site-PI for NIH funded NASH-CRN. I am the PI for many clinical trials in NASH and PSC.

Education
07/2010 - Transplant Hepatology fellowship, University of California, San Francisco
07/2009 - Gastroenterology fellowship, University of Minnesota
07/2006 - Internal Medicine Residency, University of Minnesota
M.D., 2000 - School of Medicine, Dow
Publications

  1. Tapper EB, Goldberg D, Parikh ND, Terrault NA, Welch N, Sharpton S, Hameed B, Khalili M, Stolz A, Verna EC, Brown RS, Sanyal AJ, VanWagner L, Ladner DP, Moylan CA, Diehl AM, Jones PD, Loomba RC, Dasarathy S, Simonetto DA, Shah VH, Bajaj JS, LCN Study Group. The Liver Cirrhosis Network Cohort Study: Cirrhosis Definition, Study Population, and Endpoints. The American journal of gastroenterology 2024. PMID: 39018024


  2. Gawrieh S, Vilar-Gomez E, Wilson LA, Pike F, Kleiner DE, Neuschwander-Tetri BA, Diehl AM, Dasarathy S, Kowdley KV, Hameed B, Tonascia J, Loomba R, Sanyal AJ, Chalasani N, NASH Clinical Research Network. Increases and decreases in liver stiffness measurement are independently associated with the risk of liver-related events in NAFLD. Journal of hepatology 2024. PMID: 38762169


  3. Yazdanfar M, Zepeda J, Dean R, Wu J, Levy C, Goldberg D, Lammert C, Prenner S, Reddy KR, Pratt D, Forman L, Assis DN, Lytvyak E, Montano-Loza AJ, Gordon SC, Carey EJ, Ahn J, Schlansky B, Korzenik J, Karagozian R, Hameed B, Chandna S, Yu L, Bowlus CL. African American race does not confer an increased risk of clinical events in patients with primary sclerosing cholangitis. Hepatology communications 2024. PMID: 38285883


  4. Sanyal AJ, Williams SA, Lavine JE, Neuschwander-Tetri BA, Alexander L, Ostroff R, Biegel H, Kowdley KV, Chalasani N, Dasarathy S, Diehl AM, Loomba R, Hameed B, Behling C, Kleiner DE, Karpen SJ, Williams J, Jia Y, Yates KP, Tonascia J. Defining the serum proteomic signature of hepatic steatosis, inflammation, ballooning and fibrosis in non-alcoholic fatty liver disease. Journal of hepatology 2022. PMID: 36528237


  5. Trauner M, Bowlus CL, Gulamhusein A, Hameed B, Caldwell SH, Shiffman ML, Landis C, Muir AJ, Billin A, Xu J, Liu X, Lu X, Chung C, Myers RP, Kowdley KV. Safety and sustained efficacy of the farnesoid X receptor (FXR) agonist cilofexor over a 96-week open-label extension in patients with PSC. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022. PMID: 35934287


  6. Rao A, Rule JA, Hameed B, Ganger D, Fontana RJ, Lee WM. Secular Trends in Severe Idiosyncratic Drug Induced Liver Injury in North America: An Update from the ALFSG Registry. 2022. PMID: 35081550


  7. Kwong A, Hameed B, Syed S, Ho R, Mard H, Arshad S, Ho I, Suleman T, Yao F, Mehta N. Machine learning to predict waitlist dropout among liver transplant candidates with hepatocellular carcinoma. 2022. PMID: 35029055


  8. Russo MW, Kwok R, Marina S, Ufere N, Hameed B, Chu J, Goacher E, Lingerfelt J, Terrault N, Reddy RK. Impact of the COVID-19 Pandemic on Hepatology Practice and Provider Burnout. 2021. PMID: 34783189


  9. Mazzini GS, Augustin T, Noria S, Romero-Marrero C, Li N, Hameed B, Eisenberg D, Azagury DE, Ikramuddin S. ASMBS Position Statement on the Impact of Metabolic and Bariatric Surgery on Nonalcoholic Steatohepatitis. 2021. PMID: 34953742


  10. Sanyal AJ, Van Natta ML, Clark J, Neuschwander-Tetri BA, Diehl A, Dasarathy S, Loomba R, Chalasani N, Kowdley K, Hameed B, Wilson LA, Yates KP, Belt P, Lazo M, Kleiner DE, Behling C, Tonascia J, NASH Clinical Research Network (CRN). Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease. 2021. PMID: 34670043


  11. Fix OK, Blumberg EA, Chang KM, Chu J, Chung RT, Goacher EK, Hameed B, Kaul DR, Kulik LM, Kwok RM, McGuire BM, Mulligan DC, Price JC, Reau NS, Reddy KR, Reynolds A, Rosen HR, Russo MW, Schilsky ML, Verna EC, Ward JW, Fontana RJ, AASLD COVID-19 Vaccine Working Group. American Association for the Study of Liver Diseases Expert Panel Consensus Statement: Vaccines to Prevent Coronavirus Disease 2019 Infection in Patients With Liver Disease. Hepatology (Baltimore, Md.) 2021. PMID: 33577086


  12. Fontana RJ, Stravitz RT, Durkalski V, Hanje J, Hameed B, Koch D, Ganger D, Olson J, Liou I, McGuire BM, Clasen K, Lee WM. Prognostic Value of the 13 C-Methacetin Breath Test in Adults with Acute Liver Failure and Non-acetaminophen Acute Liver Injury. 2021. PMID: 33660316


  13. Tan YQ, Wang Z, Yap QV, Chan YH, Ho RC, Hamid ARAH, Landaluce-Olavarria A, Pellino G, Gauhar V, Chand M, Wroclawski ML, Hameed BMZ, Ling SK, Sengupta S, Gallo G, Chiu PK, Tanidir Y, Tallada MPV, Garcia BN, Colleoni R, Abiddin ZAZ, Campi R, Esperto F, Carrion D, Elterman D, Chung ASJ, Ng ACF, Moschini M, Rivas JG, Mayol J, Teoh JY, Chiong E. Psychological Health of Surgeons in a Time of COVID-19: A Global Survey. 2021. PMID: 33491983


  14. Mehta N, Parikh N, Kelley RK, Hameed B, Singal AG. Surveillance and Monitoring of Hepatocellular Carcinoma During the COVID-19 Pandemic. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020. PMID: 32652308


  15. Fix OK, Hameed B, Fontana RJ, Kwok RM, McGuire BM, Mulligan DC, Pratt DS, Russo MW, Schilsky ML, Verna EC, Loomba R, Cohen DE, Bezerra JA, Reddy KR, Chung RT. Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement. Hepatology (Baltimore, Md.) 2020. PMID: 32298473


  16. Veracruz N, Hameed B, Saab S, Wong RJ. The Association Between Nonalcoholic Fatty Liver Disease and Risk of Cardiovascular Disease, Stroke, and Extrahepatic Cancers. 2020. PMID: 33679048


  17. Fels Elliott DR, Tavakol M, Lucas CH, Sheahon K, Kakar S, Hameed B, Ferrell LD, Gill RM. Clinicopathologic features and outcomes of parenchymal rejection in liver transplant biopsies. Histopathology 2020. PMID: 31894595


  18. Sheka AC, Adeyi O, Thompson J, Hameed B, Crawford PA, Ikramuddin S. Nonalcoholic Steatohepatitis: A Review. JAMA 2020. PMID: 32207804


  19. Gawrieh S, Wilson LA, Cummings OW, Clark JM, Loomba R, Hameed B, Abdelmalek MF, Dasarathy S, Neuschwander-Tetri BA, Kowdley K, Kleiner D, Doo E, Tonascia J, Sanyal A, Chalasani N. Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels. The American journal of gastroenterology 2019. PMID: 31517638


  20. Kim D, Cholankeril G, Li AA, Kim W, Tighe SP, Hameed B, Kwo PY, Harrison SA, Younossi ZM, Ahmed A. Trends in hospitalizations for chronic liver disease-related liver failure in the United States, 2005-2014. Liver international : official journal of the International Association for the Study of the Liver 2019. PMID: 31081997


  21. Trauner M, Gulamhusein A, Hameed B, Caldwell S, Shiffman ML, Landis C, Eksteen B, Agarwal K, Muir A, Rushbrook S, Lu X, Xu J, Chuang JC, Billin AN, Li G, Chung C, Subramanian GM, Myers RP, Bowlus CL, Kowdley KV. The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis. Hepatology (Baltimore, Md.) 2019. PMID: 30661255


  22. Leventhal TM, Gottfried M, Olson JC, Subramanian RM, Hameed B, Lee WM. Acetaminophen is Undetectable in Plasma From More Than Half of Patients Believed to Have Acute Liver Failure Due to Overdose. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2019. PMID: 30731196


  23. Kim D, Yoo ER, Li AA, Fernandes CT, Tighe SP, Cholankeril G, Hameed B, Ahmed A. Low-Normal Thyroid Function Is Associated With Advanced Fibrosis Among Adults in the United States. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018. PMID: 30458247


  24. Kotwani P, Saxena V, Dodge JL, Roberts J, Yao F, Hameed B. History of Marijuana Use Does Not Affect Outcomes on the Liver Transplant Waitlist. Transplantation 2018. PMID: 29319619


  25. Azeem N, Ajmera V, Hameed B, Mehta N. Hilar cholangiocarcinoma associated with immunoglobulin G4-positive plasma cells and elevated serum immunoglobulin G4 levels. Hepatology communications 2018. PMID: 29619414


  26. Stravitz RT, Gottfried M, Durkalski V, Fontana RJ, Hanje AJ, Koch D, Hameed B, Ganger D, Subramanian RM, Bukofzer S, Ravis WR, Clasen K, Sherker A, Little L, Lee WM. Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia. Hepatology (Baltimore, Md.) 2018. PMID: 29080224


  27. Hameed B, Terrault NA, Gill RM, Loomba R, Chalasani N, Hoofnagle JH, Van Natta ML. Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis. Alimentary pharmacology & therapeutics 2018. PMID: 29333665


  28. Rubin JB, Hameed B, Gottfried M, Lee WM, Sarkar M. Acetaminophen-induced Acute Liver Failure Is More Common and More Severe in Women. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2017. PMID: 29199145


  29. Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Smith A, Brown R, Crippin J, Harrison ME, Koch D, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hassanein T, Hanje AJ, Olson J, Subramanian R, Karvellas C, Hameed B, Sherker AH, Robuck P, Lee WM. Outcomes in Adults With Acute Liver Failure Between 1998 and 2013: An Observational Cohort Study. Annals of internal medicine 2016. PMID: 27043883


  30. Karvellas CJ, Tillman H, Leung AA, Lee WM, Schilsky ML, Hameed B, Stravitz RT, McGuire BM, Fix OK. Acute liver injury and acute liver failure from mushroom poisoning in North America. Liver international : official journal of the International Association for the Study of the Liver 2016. PMID: 26837055


  31. Hameed B, Terrault N. Emerging Therapies for Nonalcoholic Fatty Liver Disease. Clinics in liver disease 2016. PMID: 27063275


  32. Kelley RK, Magbanua MJ, Butler TM, Collisson EA, Hwang J, Sidiropoulos N, Evason K, McWhirter RM, Hameed B, Wayne EM, Yao FY, Venook AP, Park JW. Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls. BMC cancer 2015. PMID: 25884197


  33. Yao FY, Mehta N, Flemming J, Dodge J, Hameed B, Fix O, Hirose R, Fidelman N, Kerlan RK, Roberts JP. Downstaging of hepatocellular cancer before liver transplant: long-term outcome compared to tumors within Milan criteria. Hepatology (Baltimore, Md.) 2015. PMID: 25689978


  34. Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E. Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial. Lancet (London, England) 2014. PMID: 25468160


  35. Yao FY, Hameed B, Mehta N, Roberts JP. Response to letter to the editors. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2014. PMID: 25155484


  36. Sharpton SR, Feng S, Hameed B, Yao F, Lai JC. Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes. Transplantation 2014. PMID: 24717221


  37. Hameed B, Mehta N, Sapisochin G, Roberts JP, Yao FY. Alpha-fetoprotein level > 1000 ng/mL as an exclusion criterion for liver transplantation in patients with hepatocellular carcinoma meeting the Milan criteria. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2014. PMID: 24797281


  38. Mendelsohn BA, Mehta N, Hameed B, Pekmezci M, Packman S, Ralph J. Adult-Onset Fatal Neurohepatopathy in a Woman Caused by MPV17 Mutation. JIMD reports 2013. PMID: 24190800


  39. Noureddin M, Yates KP, Vaughn IA, Neuschwander-Tetri BA, Sanyal AJ, McCullough A, Merriman R, Hameed B, Doo E, Kleiner DE, Behling C, Loomba R. Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients. Hepatology (Baltimore, Md.) 2013. PMID: 23686698


  40. Hassan A, Hameed B, Islam M, Khealani B, Khan M, Shafqat S. Clinical predictors of EMG-confirmed cervical and lumbosacral radiculopathy. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2013. PMID: 23419571


  41. Brandman D, Biggins SW, Hameed B, Roberts JP, Terrault NA. Pretransplant severe hepatic encephalopathy, peritransplant sodium and post-liver transplantation morbidity and mortality. Liver international : official journal of the International Association for the Study of the Liver 2011. PMID: 22098119


  42. Vagefi PA, Klein I, Gelb B, Hameed B, Moff SL, Simko JP, Fix OK, Eilers H, Feiner JR, Ascher NL, Freise CE, Bass NM. Emergent orthotopic liver transplantation for hemorrhage from a giant cavernous hepatic hemangioma: case report and review. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010. PMID: 20549381


  43. Kazim SF, Islam M, Khan M, Hameed B, Shafqat S. Risk of multiple sclerosis after idiopathic optic neuritis in a Pakistani population. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2010. PMID: 20437939


  44. Hameed B, Lake JR. Using higher risk organs for liver transplantation: in whom and at what price? Gastroenterology 2008. PMID: 18851971


  45. Khealani BA, Hameed B, Mapari UU. Stroke in Pakistan. JPMA. The Journal of the Pakistan Medical Association 2008. PMID: 18988415


  46. Hameed B, Khealani BA, Mozzafar T, Wasay M. Prognostic indicators in patients with primary intraventricular haemorrhage. JPMA. The Journal of the Pakistan Medical Association 2005. PMID: 16164155