Monica Fung, MD

Assoc Prof of Clin Medicine

CLINICAL ACTIVITIES
Monica Fung specializes in infectious diseases with a focus on patients with compromised immune systems, including those with solid organ or stem cell transplants. She attends on the Immunocompromised and General Infectious Diseases Consult Services, and has clinics in the 360 Wellness Center and Infectious Diseases Faculty Practice at UCSF-Parnassus.

RESEARCH AND EDUCATIONAL PURSUITS
Monica serves as Co-Director of the Transplant/Immunocompromised Host Infectious Diseases Program. Her research focuses the application of novel diagnostics to improve diagnosis of infections among transplant recipients. She directs the Transplant/Immunocompromised Host track within the UCSF Infectious Diseases Fellowship Program, and serves as a small group leader for the Pathogen Host Defense course in the School of Medicine.

Education
Fellowship, 2018 - Infectious Diseases, UCSF
Residency, 2016 - Internal Medicine, Beth Israel Deaconess Medical Center
M.D., 2013 - , Harvard Medical School
M.P.H., 2013 - , Harvard School of Public Health
Publications

  1. Madut DB, Chemaly RF, Dadwal SS, Hill JA, Lee YJ, Haidar G, Luk A, Drelick A, Chin-Hong PV, Benamu E, Khawaja F, Nanayakkara D, Papanicolaou GA, Small CB, Fung M, Barron M, Davis T, McClain MT, Maziarz EK, Bedoya AD, Gilstrap DL, Todd JL, Barkauskas CE, Heldman MR, Bigelow R, Leimberger JD, Tsalik EL, Wolf O, Mughar M, Lau C, Noll N, Hollemon D, Duttagupta R, Lupu DS, Bercovici S, Perkins BA, Blauwkamp TA, Fowler VG, Holland TL, Bergin SP. Clinical Utility of Plasma Microbial Cell-Free DNA Sequencing Among Immunocompromised Patients With Pneumonia. Open forum infectious diseases 2024. PMID: 39091643


  2. Fung M, Patel N, DeVoe C, Ryan CN, McAdams S, Pamula M, Dwivedi A, Teraoka J, Smollin M, Sam S, Perkins B, Chin-Hong P. Utility of Serial Microbial Cell-free DNA Sequencing for Inpatient and Outpatient Pathogen Surveillance Among Allogeneic Hematopoietic Stem Cell Transplant Recipients. Open forum infectious diseases 2024. PMID: 39086465


  3. Fung M, La Hoz RM, Durand CM, Lee DH, Sears D, Hohe C, Chin-Hong P, Roberts JP. Successful Living Donor Liver Transplant from Donor with False-Positive HIV Test in Recipient without HIV. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2024. PMID: 38705516


  4. Bergin SP, Chemaly RF, Dadwal SS, Hill JA, Lee YJ, Haidar G, Luk A, Drelick A, Chin-Hong PV, Benamu E, Khawaja F, Nanayakkara D, Papanicolaou GA, Small CB, Fung M, Barron MA, Davis T, McClain MT, Maziarz EK, Madut DB, Bedoya AD, Gilstrap DL, Todd JL, Barkauskas CE, Bigelow R, Leimberger JD, Tsalik EL, Wolf O, Mughar M, Hollemon D, Duttagupta R, Lupu DS, Bercovici S, Perkins BA, Blauwkamp TA, Fowler VG, Holland TL. Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023. PMID: 37815489


  5. Lueking R, Fung M, Ramos-Salazar E, Katari S, Funk GA, Wolfe CR, La Hoz RM. Challenging Boundaries: Organ Transplants from Donors with Listeria Central Nervous System Infections. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2024. PMID: 38431076


  6. Langelier C, Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, Rouphael N, Higuita N, Atkinson M, Breckenridge S, Fung M, Messer W, Network I, Salehi-Rad R, Altman M, Becker P, Bosinger S, Eckalbar W, Hoch A, Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein S, Krammer F, Maecker H, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed E. Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. Research square 2023. PMID: 38196658


  7. Mulliken JS, Hampshire KN, Rappold AG, Fung M, Babik JM, Doernberg SB. Risk of systemic fungal infections after exposure to wildfires: a population-based, retrospective study in California. The Lancet. Planetary health 2023. PMID: 37164514


  8. Sweeney DA, Tuyishimire B, Ahuja N, Beigel JH, Beresnev T, Cantos VD, Castro JG, Cohen SH, Cross K, Dodd LE, Erdmann N, Fung M, Ghazaryan V, George SL, Grimes KA, Hynes NA, Julian KG, Kandiah S, Kim HJ, Levine CB, Lindholm DA, Lye DC, Maves RC, Oh MD, Paules C, Rapaka RR, Short WR, Tomashek KM, Wolfe CR, Kalil AC. Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections. Open forum infectious diseases 2023. PMID: 37206623


  9. Roland LT, Humphreys IM, Le CH, Babik JM, Bailey CE, Ediriwickrema LS, Fung M, Lieberman JA, Magliocca KR, Nam HH, Teo NW, Thomas PC, Winegar BA, Birkenbeuel JL, David AP, Goshtasbi K, Johnson PG, Martin EC, Nguyen TV, Patel NN, Qureshi HA, Tay K, Vasudev M, Abuzeid WM, Hwang PH, Jafari A, Russell MS, Turner JH, Wise SK, Kuan EC. Diagnosis, prognosticators, and management of acute invasive fungal rhinosinusitis: multidisciplinary consensus statement and Evidence-Based review with recommendations. International forum of allergy & rhinology 2023. PMID: 36680469


  10. Katrak S, Han E, Readhead A, Fung M, Keh C, Flood J, Barry P. Solid organ transplant recipients with tuberculosis disease in California, 2010 to 2020. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2022. PMID: 36695700


  11. Fung M, DeVoe C, Spottiswoode N, Doernberg SB. Maribavir for Cytomegalovirus Treatment in the Real World-Not a Silver Bullet. Open forum infectious diseases 2022. PMID: 36632422


  12. DeVoe C, Pandey S, Shariff D, Arora S, Henrich TJ, Yokoe DS, Langelier CR, Servellita V, Chiu C, Miller S, Babik JM, Chin-Hong P, Fung M. COVID-19 in Vaccinated Versus Unvaccinated Hematologic Malignancy Patients. 2022. PMID: 35426225


  13. Serpa PH, Deng X, Abdelghany M, Crawford E, Malcolm K, Caldera S, Fung M, McGeever A, Kalantar KL, Lyden A, Ghale R, Deiss T, Neff N, Miller SA, Doernberg SB, Chiu CY, DeRisi JL, Calfee CS, Langelier CR. Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections. Genome medicine 2022. PMID: 35818068


  14. Chan JL, Nazarian E, Musser KA, Snavely EA, Fung M, Doernberg SB, Pouch SM, Leekha S, Anesi JA, Kodiyanplakkal RP, Turbett SE, Walters MS, Epstein L. Prevalence of carbapenemase-producing organisms among hospitalized solid organ transplant recipients, five U.S. hospitals, 2019-2020. 2022. PMID: 34989092


  15. Crossman H, Guterman E, Fung M. Delayed diagnosis and treatment of secondary syphilis in pancreas-kidney transplant recipient: Need for increased awareness of sexually transmitted infections in solid organ transplantation. 2021. PMID: 34797024


  16. Mehta N, Gerdts J, Fung M, Guterman EL. Brain Abscess Caused by Bordetella hinzii. 2021. PMID: 34840911


  17. Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF. Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019. Open forum infectious diseases 2021. PMID: 34405093


  18. Plonowska-Hirschfeld KA, Fung M, Glastonbury C, Ha PK. Parapharyngeal tuberculoid mass: A rare complication of Bacillus Calmette-Guérin therapy for urothelial carcinoma in situ. Clinical case reports 2021. PMID: 34194767


  19. Bond AR, Bainbridge E, Doernberg SB, Babik JM, Miller S, Khanafshar E, Henry T, David A, Russell M, Brandman D, Sherman CB, Yao F, Fung M. Disseminated Legionella micdadei Infection in a Liver Transplant Patient Presenting as Pulmonary Nodules and a Laryngeal Lesion. Transplant infectious disease : an official journal of the Transplantation Society 2021. PMID: 33434394


  20. Fung M, Babik JM. COVID-19 in Immunocompromised Hosts: What We Know So Far. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021. PMID: 33501974


  21. June L Chan, Elizabeth Nazarian, Kimberlee A Musser, Monica Fung, Sarah B Doernberg, Stephanie M Pouch, Stephanie M Pouch, Surbhi Leekha, Judith A Anesi, Rosy Priya Kodiyanplakkal, Sarah Turbett, Maroya Spalding Walters, Lauren Epstein, Lauren Epstein. 918. Pilot Surveillance for Carbapenemase Gene-positive Organisms Among Hospitalized Solid Organ Transplant Recipients. Open forum infectious diseases 2020. PMID:


  22. Fung M, Otani I, Pham M, Babik J. Zoonotic coronavirus epidemics: Severe acute respiratory syndrome, Middle East respiratory syndrome, and coronavirus disease 2019. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2020. PMID: 33310180


  23. Fung M, Nambiar A, Pandey S, Aldrich JM, Teraoka J, Freise C, Roberts J, Chandran S, Hays SR, Bainbridge E, DeVoe C, Gardner AR, Yokoe D, Henrich TJ, Babik JM, Chin-Hong P. Treatment of Immunocompromised COVID-19 patients with Convalescent Plasma. Transplant infectious disease : an official journal of the Transplantation Society 2020. PMID: 32989856


  24. Iasella CJ, Hoji A, Popescu I, Wei J, Snyder M, Zhang Y, Xu W, Iouchmanov V, Koshy R, Brown M, Fung M, Langelier C, Lendermon EA, Dugger D, Shah R, Lee J, Johnson B, Golden J, Leard LE, Kleinhenz ME, Kilaru S, Hays SR, Singer JP, Sanchez PG, Morrell MR, Pilewski JM, Greenland JR, Chen K, McDyer JF. Type-1 Immunity and Endogenous Immune Regulators Predominate in the Airway Transcriptome during Chronic Lung Allograft Dysfunction. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020. PMID: 33078555


  25. Dugger DT, Fung M, Hays SR, Singer JP, Ellen Kleinhenz M, Leard LE, Golden JA, Shah RJ, Lee JS, Deiter F, Greenland NY, Jones KD, Langelier CR, Greenland JR. Chronic Lung Allograft Dysfunction Small Airways Reveal A Lymphocytic Inflammation Gene Signature. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020. PMID: 32885581


  26. Dugger DT, Fung M, Zlock L, Caldera S, Sharp L, Hays SR, Singer JP, Leard LE, Golden JA, Shah RJ, Kukreja J, Gordon E, Finkbeiner W, Kleinhenz ME, Langelier C, Greenland JR. Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection. Cell reports. Medicine 2020. PMID: 32754722


  27. Fung M, Chiu CY, DeVoe C, Doernberg SB, Schwartz BS, Langelier C, Henrich TJ, Yokoe D, Davis J, Hays SR, Chandran S, Kukreja J, Ng D, Prostko J, Taylor R, Reyes K, Bainbridge E, Bond A, Chin-Hong P, Babik JM. Clinical Outcomes and Serologic Response in Solid Organ Transplant Recipients with COVID-19: A Case Series from the United States. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2020. PMID: 32476258


  28. D.T. Dugger, M. Fung, L. Zlock, S. Caldera, S.R. Hays, J.P. Singer, L.E. Leard, J.A. Golden, R. Shah, J. Kukreja, W. Finkbeiner, M. Kleinhenz, C. Langelier, J.R. Greenland. Decreased Immune Activation in Cystic Fibrosis Airway Epithelium Following Lung Transplant. The Journal of Heart and Lung Transplantation 2020. PMID:


  29. Langelier C, Fung M, Caldera S, Deiss T, Lyden A, Prince BC, Hayakawa Serpa P, Moazed F, Chin-Hong P, DeRisi JL, Calfee CS. Detection of Pneumonia Pathogens from Plasma Cell-Free DNA. American journal of respiratory and critical care medicine 2019. PMID: 31647702


  30. Fung M, Babik J, Humphreys IM, Davis GE. Diagnosis and Treatment of Acute Invasive Fungal Sinusitis in Cancer and Transplant Patients. Current infectious disease reports 2019. PMID: 31773398


  31. Fung M, Jacobsen E, Freedman A, Prestes D, Farmakiotis D, Gu X, Nguyen PL, Koo S. Increased Risk of Infectious Complications in Older Patients With Indolent Non-Hodgkin Lymphoma Exposed to Bendamustine. Volume 68 of Issue 2. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019. PMID: 29800121


  32. Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults. Proceedings of the National Academy of Sciences of the United States of America 2018. PMID: 30482864


  33. Fung M, Zompi S, Seng H, Hollemon D, Parham A, Hong DK, Bercovici S, Dolan E, Lien K, Teraoka J, Logan AC, Chin-Hong P. Plasma Cell-Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients. Open forum infectious diseases 2018. PMID: 30581881


  34. Fung M, Schwartz BS, Doernberg SB, Langelier C, Lo M, Graff L, Tan M, Logan AC, Chin-Hong P, Babik JM. Breakthrough Invasive Fungal Infections on Isavuconazole Prophylaxis and Treatment: What is Happening in the Real-world Setting? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018. PMID: 29617983


  35. Miller DC, Fung M, Carbo A. A Furry Friend's Dirty Mouth: Brain Abscess Due to Aggregatibacter (Haemophilus) aphrophilus. Volume 130 of Issue 10. The American journal of medicine 2017. PMID: 28528922


  36. Monica Fung, Arnold Freedman, Daniel Prestes, Xiangmei Gu, Dimitrios Farmakiotis, Paul Nguyen, Sophia Koo. Infectious Complications Associated with Bendamustine Exposure in Patients with Indolent non-Hodgkin Lymphoma. Open forum infectious diseases 2016. PMID:


  37. Sandora TJ, Fung M, Melvin P, Graham DA, Rangel SJ. National Variability and Appropriateness of Surgical Antibiotic Prophylaxis in US Children's Hospitals. Volume 170 of Issue 6. JAMA pediatrics 2016. PMID: 27088649


  38. Fung M, Kim J, Marty FM, Schwarzinger M, Koo S. Meta-Analysis and Cost Comparison of Empirical versus Pre-Emptive Antifungal Strategies in Hematologic Malignancy Patients with High-Risk Febrile Neutropenia. Volume 10 of Issue 11. PloS one 2015. PMID: 26554923


  39. Sandora TJ, Fung M, Flaherty K, Helsing L, Scanlon P, Potter-Bynoe G, Gidengil CA, Lee GM. Epidemiology and risk factors for Clostridium difficile infection in children. Volume 30 of Issue 7. The Pediatric infectious disease journal 2011. PMID: 21233782


  40. Rangel SJ, Fung M, Graham DA, Ma L, Nelson CP, Sandora TJ. Recent trends in the use of antibiotic prophylaxis in pediatric surgery. Volume 46 of Issue 2. Journal of pediatric surgery 2011. PMID: 21292089


  41. Fung M, Scott KC, Kent CK, Klausner JD. Chlamydial and gonococcal reinfection among men: a systematic review of data to evaluate the need for retesting. Volume 83 of Issue 4. Sexually transmitted infections 2006. PMID: 17166889