Publications

Department of Medicine faculty members published more than 3,000 peer-reviewed articles in 2022.

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Journal of viral hepatitis

Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B.

2019

Authors: Di Bisceglie AM, King WC, Lisker-Melman M, Khalili M, Belle SH, Feld JJ, Ghany MG, Janssen HLA, Lau D, Lee WM, Ling SC, Cooper S, Rosenthal P, Schwarz KB, Sterling RK, Teckman JH, Terrault N

Health promotion practice

Developing Tobacco Control Interventions in Permanent Supportive Housing for Formerly Homeless Adults.

2019

Authors: Alizaga NM, Nguyen T, Petersen AB, Elser H, Vijayaraghavan M

ACR Open Rheumatology

Differences in Longitudinal Disease Activity Between Research Cohort and Noncohort Participants with Rheumatoid Arthritis Using Electronic Health Record Data.

2019

Authors: Gianfrancesco MA, Trupin L, McCulloch CE, Shiboski S, Schmajuk G, Yazdany J

EVALUATION AND MANAGEMENT OF EXPOSURE TO INFECTIOUS AGENTS.

2019

Authors:

JACC. Heart failure

Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey.

2019

Authors: Psotka MA, Ammon SE, Fiuzat M, Bozkurt B, Chung ES, Cole RT, Greene SJ, Kraus D, Ky B, McIlvennan CK, Shah P, Teerlink JR, Walsh MN, Jessup M, O'Connor CM

The Annals of thoracic surgery

Hemolysis and Non-Hemorrhagic Stroke during Venoarterial Extracorporeal Membrane Oxygenation.

2019

Authors: Saeed O, Jakobleff WA, Forest SJ, Chinnadurai T, Mellas N, Rangasamy S, Xia Y, Madan S, Acharya P, Algodi M, Patel SR, Shin J, Vukelic S, Sims DB, Gil MR, Billett HH, Kizer JR, Goldstein DJ, Jorde UP

Volume 321 of Issue 14 | JAMA

Reducing Emergency Department Length of Stay.

2019

Authors: Mercer MP, Singh MK, Kanzaria HK

Volume 365 | BMJ (Clinical research ed.)

Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis.

2019

Authors: Levis B, Benedetti A, Thombs BD, DEPRESsion Screening Data (DEPRESSD) Collaboration

View Abstract

OBJECTIVE

To determine the accuracy of the Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression.

DESIGN

Individual participant data meta-analysis.

DATA SOURCES

Medline, Medline In-Process and Other Non-Indexed Citations, PsycINFO, and Web of Science (January 2000-February 2015).

INCLUSION CRITERIA

Eligible studies compared PHQ-9 scores with major depression diagnoses from validated diagnostic interviews. Primary study data and study level data extracted from primary reports were synthesized. For PHQ-9 cut-off scores 5-15, bivariate random effects meta-analysis was used to estimate pooled sensitivity and specificity, separately, among studies that used semistructured diagnostic interviews, which are designed for administration by clinicians; fully structured interviews, which are designed for lay administration; and the Mini International Neuropsychiatric (MINI) diagnostic interviews, a brief fully structured interview. Sensitivity and specificity were examined among participant subgroups and, separately, using meta-regression, considering all subgroup variables in a single model.

RESULTS

Data were obtained for 58 of 72 eligible studies (total n=17 357; major depression cases n=2312). Combined sensitivity and specificity was maximized at a cut-off score of 10 or above among studies using a semistructured interview (29 studies, 6725 participants; sensitivity 0.88, 95% confidence interval 0.83 to 0.92; specificity 0.85, 0.82 to 0.88). Across cut-off scores 5-15, sensitivity with semistructured interviews was 5-22% higher than for fully structured interviews (MINI excluded; 14 studies, 7680 participants) and 2-15% higher than for the MINI (15 studies, 2952 participants). Specificity was similar across diagnostic interviews. The PHQ-9 seems to be similarly sensitive but may be less specific for younger patients than for older patients; a cut-off score of 10 or above can be used regardless of age..

CONCLUSIONS

PHQ-9 sensitivity compared with semistructured diagnostic interviews was greater than in previous conventional meta-analyses that combined reference standards. A cut-off score of 10 or above maximized combined sensitivity and specificity overall and for subgroups.