Volume 19 of Issue 8 | Pharmacogenomics
Authors: Turner S, Francis B, Wani N, Vijverberg S, Pino-Yanes M, Mukhopadhyay S, Tavendale R, Palmer C, Burchard EG, Merid SK, Melén E, Maitland-van der Zee AH, The Pharmacogenomics In Childhood Asthma Consortium OBO
Our hypothesis was that children with mutations in genes coding for glutathione S-transferases (GST) have worse asthma outcomes compared with children with active type genotype. Data were collected in five populations. The rs1695 single nucleotide polymorphism (GSTP1) was determined in all cohorts (3692 children) and GSTM1 and GSTT1 null genotype were determined in three cohorts (2362 children). GSTT1 null (but not other genotypes) was associated with a minor increased risk for asthma attack and there were no significant associations between GST genotypes and asthma severity. Interactions between GST genotypes and SHS exposure or asthma severity with the study outcomes were nonsignificant. We find no convincing evidence that the GST genotypes studied are related to asthma outcomes.
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Journal of the Formosan Medical Association = Taiwan yi zhi
Authors: Kao CC, Yang WS, Fang JT, Liu KD, Wu VC
BMC medicine
Authors: Murthy SE, Chatterjee F, Crook A, Dawson R, Mendel C, Murphy ME, Murray SR, Nunn AJ, Phillips PPJ, Singh KP, McHugh TD, Gillespie SH
American Society of Gastrointestinal Endoscopy’s Gastrointestinal Endoscopy Self-Assessment Program (GESAP) IX.
Authors: Nett AS, ASGE Working Group.
Arthritis care & research
Authors: Yelin E, Trupin L, Bunde J, Yazdany J
Authors: Mariam T. Nawas, Charalambos Andreadis, Thomas G. Martin, Jeffrey Lee Wolf, Weiyun Z. Ai, Lawrence D. Kaplan, Gabriel N. Mannis, Aaron Logan, Lloyd Earl Damon, Chiung-Yu Huang, Rebecca L. Olin
Authors: Sara Nunnery, Dorothy Wang, Marisela Tan, Richard Fong, Mimi Ming Lo, Rebecca L. Olin
Journal of Clinical Oncology
Authors: Mark J. Levis, Catherine Choy Smith, Koji Ishizuka, Ken Kobayashi, Meena Arunachalam, Yibin Wang, Deborah Lazzaretto, Jorge E. Cortes
Journal of Clinical Oncology
Authors: Zhuoer Xie, Neil Wenger, Liliana Johansen, David Elashoff, Jacqueline Trent, Kristina Lee, Celia Kaplan, Lisa Madlensky, Tracy M. Layton, Antonia Petruse, Arash Naeim