American journal of respiratory and critical care medicine
Authors: Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy SL, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade SM, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Ware LB, Palmer SM, Christie JD
Annals of epidemiology
Authors: Odden MC, Tager IB, Gansevoort RT, Bakker SJ, Fried LF, Newman AB, Katz R, Satterfield S, Harris TB, Sarnak MJ, Siscovick D, Shlipak MG
Intensive care medicine
Authors: Schultz MJ, Juffermans NP, Matthay MA
AIDS research and treatment
Authors: Ippolito G, Levy JA, Sonnerborg A, Mugusi F, Dianzani F
Volume 368 of Issue 2 | The New England journal of medicine
Authors: Ardaugh BM, Graves SE, Redberg RF
Journal of the American College of Cardiology
Authors: Marcus GM, Keung E, Scheinman MM
JAMA
Authors: Calhoun WJ, Boushey HA, Ameredes BT
Volume 5 of Issue 167 | Science translational medicine
Authors: Friedman SL, Sheppard D, Duffield JS, Violette S
Fibrosis, or the accumulation of extracellular matrix molecules that make up scar tissue, is a common feature of chronic tissue injury. Pulmonary fibrosis, renal fibrosis, and hepatic cirrhosis are among the more common fibrotic diseases, which in aggregate represent a huge unmet clinical need. New appreciation of the common features of fibrosis that are conserved among tissues has led to a clearer understanding of how epithelial injury provokes dysregulation of cell differentiation, signaling, and protein secretion. At the same time, discovery of tissue-specific features of fibrogenesis, combined with insights about genetic regulation of fibrosis, has laid the groundwork for biomarker discovery and validation, and the rational identification of mechanism-based antifibrotic drugs. Together, these advances herald an era of sustained focus on translating the biology of fibrosis into meaningful improvements in quality and length of life in patients with chronic fibrosing diseases.
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Authors: Louie J, Yang S, Schechter R
Annals of the rheumatic diseases
Authors: Bernatsky S, Ramsey-Goldman R, Joseph L, Boivin JF, Costenbader KH, Urowitz MB, Gladman DD, Fortin PR, Nived O, Petri MA, Jacobsen S, Manzi S, Ginzler EM, Isenberg D, Rahman A, Gordon C, Ruiz-Irastorza G, Yelin E, Bae SC, Wallace DJ, Peschken CA, Dooley MA, Edworthy SM, Aranow C, Kamen DL, Romero-Diaz J, Askanase A, Witte T, Barr SG, Criswell LA, Sturfelt GK, Blanco I, Feldman CH, Dreyer L, Patel NM, St Pierre Y, Clarke AE