Publications

Department of Medicine faculty members published more than 3,000 peer-reviewed articles in 2022.

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Kidney international

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease.

2011

Authors: Isakova T, Wahl P, Vargas GS, Gutiérrez OM, Scialla J, Xie H, Appleby D, Nessel L, Bellovich K, Chen J, Hamm L, Gadegbeku C, Horwitz E, Townsend RR, Anderson CA, Lash JP, Hsu CY, Leonard MB, Wolf M

JAMA

Reporting of conflicts of interest in meta-analyses of trials of pharmacological treatments.

2011

Authors: Roseman M, Milette K, Bero LA, Coyne JC, Lexchin J, Turner EH, Thombs BD

Patient education and counseling

A computerized education module improves patient knowledge and attitudes about appropriate antibiotic use for acute respiratory tract infections.

2011

Authors: Price EL, Mackenzie TD, Metlay JP, Camargo CA, Gonzales R

Heart rhythm

Isolated septal substrate for ventricular tachycardia in nonischemic dilated cardiomyopathy: incidence, characterization, and implications.

2011

Authors: Haqqani HM, Tschabrunn CM, Tzou WS, Dixit S, Cooper JM, Riley MP, Lin D, Hutchinson MD, Garcia FC, Bala R, Verdino RJ, Callans DJ, Gerstenfeld EP, Zado ES, Marchlinski FE

European heart journal

Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study.

2011

Authors: Metra M, O'Connor CM, Davison BA, Cleland JG, Ponikowski P, Teerlink JR, Voors AA, Givertz MM, Mansoor GA, Bloomfield DM, Jia G, DeLucca P, Massie B, Dittrich H, Cotter G

European heart journal

Cardiac inotropes: current agents and future directions.

2011

Authors: Hasenfuss G, Teerlink JR

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers.

2011

Authors: Falcone M, Jepson C, Benowitz N, Bergen AW, Pinto A, Wileyto EP, Baldwin D, Tyndale RF, Lerman C, Ray R

Volume 12 of Issue 3 | The pharmacogenomics journal

Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.

2011

Authors: Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM

View Abstract

ATP-binding cassette (ABC) membrane transporters determine the disposition of many drugs, metabolites and endogenous compounds. Coding region variation in ABC transporters is the cause of many genetic disorders, but much less is known about the genetic basis and functional outcome of ABC transporter expression level variation. We used genotype and mRNA transcript level data from human lymphoblastoid cell lines to assess population and gender differences in ABC transporter expression, and to guide the discovery of genomic regions involved in transcriptional regulation. Nineteen of 49 ABC genes were differentially expressed between individuals of African, Asian and European descent, suggesting an important influence of race on expression level of ABC transporters. Twenty-four significant associations were found between transporter transcript levels and proximally located genetic variants. Several of the associations were experimentally validated in reporter assays. Through influencing ABC expression levels, these single-nucleotide polymorphisms may affect disease susceptibility and response to drugs.

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Cancer

A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma.

2011

Authors: Harzstark AL, Small EJ, Weinberg VK, Sun J, Ryan CJ, Lin AM, Fong L, Brocks DR, Rosenberg JE

Critical care (London, England)

Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status.

2011

Authors: Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P, Ely EW