Virology
Authors: Xiao J, Palefsky JM, Herrera R, Sunshine C, Tugizov SM
Neuroscience
Authors: Crane JM, Tajima M, Verkman AS
Journal of the American College of Surgeons
Authors: Silverstein MJ, Recht A, Lagios MD, Bleiweiss IJ, Blumencranz PW, Gizienski T, Harms SE, Harness J, Jackman RJ, Klimberg VS, Kuske R, Levine GM, Linver MN, Rafferty EA, Rugo H, Schilling K, Tripathy D, Vicini FA, Whitworth PW, Willey SC
Journal of the American Society of Nephrology : JASN
Authors: Frassetto LA, Hsu CY
Volume 464 of Issue 3 | Neuroscience letters
Authors: Gear RW, Levine JD
The ascending nociceptive control (ANC), a novel spinostriatal pain modulation pathway, mediates a form of pain-induced analgesia referred to as noxious stimulus-induced antinociception (NSIA). ANC includes specific spinal cord mechanisms as well as circuitry in nucleus accumbens, a major component of the ventral striatum. Here, using the trigeminal jaw-opening reflex (JOR) in the rat as a nociceptive assay, we show that microinjection of the nicotinic acetylcholine receptor (nAChR) antagonist mecamylamine into the rostral ventral medulla (RVM) blocks NSIA, implicating RVM as a potentially important link between ANC and the PAG-RVM-spinal descending pain modulation system. A circuit connecting nucleus accumbens to the RVM is proposed as a novel striato-RVM pathway.
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Kidney international
Authors: Kestenbaum BR, Adeney KL, de Boer IH, Ix JH, Shlipak MG, Siscovick DS
Volume 302 of Issue 7 | JAMA
Authors: Munster PN, Carpenter JT
Surgical endoscopy
Authors: Ramamoorthy SL, Lee JK, Luo L, Mintz Y, Cullen J, Easter DW, Savu MK, Chock A, Carethers J, Horgan S, Talamini MA
Breast cancer research and treatment
Authors: Natrajan R, Weigelt B, Mackay A, Geyer FC, Grigoriadis A, Tan DS, Jones C, Lord CJ, Vatcheva R, Rodriguez-Pinilla SM, Palacios J, Ashworth A, Reis-Filho JS
Annals of internal medicine
Authors: Van Allen EM, Kohlwes RJ