Publications

Department of Medicine faculty members published more than 3,000 peer-reviewed articles in 2022.

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Journal of diabetes science and technology

The artificial pancreas: how sweet engineering will solve bitter problems.

2007

Authors: Klonoff DC

Clinical therapeutics

Metabolic effects of two years of exenatide treatment on diabetes, obesity, and hepatic biomarkers in patients with type 2 diabetes: an interim analysis of data from the open-label, uncontrolled extension of three double-blind, placebo-controlled trials.

2007

Authors: Buse JB, Klonoff DC, Nielsen LL, Guan X, Bowlus CL, Holcombe JH, Maggs DG, Wintle ME

Journal of diabetes science and technology

Benefits and limitations of self-monitoring of blood glucose.

2007

Authors: Klonoff DC

Clinical pharmacology and therapeutics

Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein.

2007

Authors: de Jong FA, Scott-Horton TJ, Kroetz DL, McLeod HL, Friberg LE, Mathijssen RH, Verweij J, Marsh S, Sparreboom A

Volume 2 of Issue 10 | Nature protocols

Integration of biological networks and gene expression data using Cytoscape.

2007

Authors: Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, Workman C, Christmas R, Avila-Campilo I, Creech M, Gross B, Hanspers K, Isserlin R, Kelley R, Killcoyne S, Lotia S, Maere S, Morris J, Ono K, Pavlovic V, Pico AR, Vailaya A, Wang PL, Adler A, Conklin BR, Hood L, Kuiper M, Sander C, Schmulevich I, Schwikowski B, Warner GJ, Ideker T, Bader GD

View Abstract

Cytoscape is a free software package for visualizing, modeling and analyzing molecular and genetic interaction networks. This protocol explains how to use Cytoscape to analyze the results of mRNA expression profiling, and other functional genomics and proteomics experiments, in the context of an interaction network obtained for genes of interest. Five major steps are described: (i) obtaining a gene or protein network, (ii) displaying the network using layout algorithms, (iii) integrating with gene expression and other functional attributes, (iv) identifying putative complexes and functional modules and (v) identifying enriched Gene Ontology annotations in the network. These steps provide a broad sample of the types of analyses performed by Cytoscape.

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Evidence report/technology assessment