Journal of Social and Personal Relationships
Authors: Gamarel KE, Sevelius JM, Reisner SL, Coats CS, Nemoto T, Operario D
JAMA
Authors: Saag MS, Benson CA, Gandhi RT, Hoy JF, Landovitz RJ, Mugavero MJ, Sax PE, Smith DM, Thompson MA, Buchbinder SP, Del Rio C, Eron JJ, Fätkenheuer G, Günthard HF, Molina JM, Jacobsen DM, Volberding PA
Caries research
Authors: Martinez-Mier EA, Tenuta LMA, Carey CM, Cury JA, van Loveren C, Ekstrand KR, Ganss C, Schulte A, Baig A, Benzian H, Bottenberg P, Buijs MJ, Ceresa A, Carvalho JC, Ellwood R, González-Cabezas C, Holmgren C, Knapp M, Lippert F, Joiner A, Manton DJ, Martignon S, Mason S, Jablonski-Momeni A, Plett W, Rahiotis C, Sampaio F, Zero DT
Annals of internal medicine
Authors: Keyhani S, Steigerwald S, Ishida J, Vali M, Cerdá M, Hasin D, Dollinger C, Yoo SR, Cohen BE
Annals of internal medicine
Authors: Liu P, Dhruva SS, Shah ND, Ross JS
JAMA
Authors: Holmgren AJ, Adler-Milstein J, Chen LM
Volume 8 of Issue 8 | European heart journal. Acute cardiovascular care
Authors: Watson RA, Bohula EA, Gilliland TC, Sanchez PA, Berg DD, Morrow DA
BACKGROUND
The changing landscape of care in the Cardiac Intensive Care Unit (CICU) has prompted efforts to redesign the structure and organization of advanced CICUs. Few studies have quantitatively characterized current demographics, diagnoses, and outcomes in the contemporary CICU.
METHODS
We evaluated patients in a prospective observational database, created to support quality improvement and clinical care redesign in an AHA Level 1 (advanced) CICU at Brigham and Women's Hospital, Boston, MA, USA. All consecutive patients (=2193) admitted from 1 January 2015 to 31 December 2017 were included at the time of admission to the CICU.
RESULTS
The median age was 65 years (43% >70 years) and 44% of patients were women. Non-cardiovascular comorbidities were common, including chronic kidney disease (27%), pulmonary disease (22%), and active cancer (13%). Only 7% of CICU admissions were primarily for an acute coronary syndrome, which was the seventh most common individual diagnosis. The top three reasons for admission to the CICU were shock/hypotension (26%), cardiopulmonary arrest (11%), or primary arrhythmia without arrest (9%). Respiratory failure was a primary or major secondary reason for triage to the CICU in 17%. In-hospital mortality was 17.6%.
CONCLUSIONS
In a tertiary, academic, advanced CICU, patients are elderly with a high burden of non-cardiovascular comorbid conditions. Care has shifted from ACS toward predominantly shock and cardiac arrest, as well as non-ischemic conditions, and the mortality of these conditions is high. These data may be useful to guide cardiac critical care redesign.
View on PubMed
Biology open
Authors: Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Authors: Van Blarigan EL, Ou FS, Niedzwiecki D, Zhang S, Fuchs CS, Saltz L, Mayer RJ, Venook A, Ogino S, Song M, Benson A, Hantel A, Atkins JN, Giovannucci EL, Meyerhardt JA
Arthritis care & research
Authors: Aringer M, Daikh DI